Changing patterns in medication prescription for gestational diabetes during a time of guideline change in the USA: a cross-sectional study.

ABSTRACT:

Objective

To define patterns of prescription and factors associated with choice of pharmacotherapy for gestational diabetes mellitus (GDM), namely metformin, glyburide and insulin, during a period of evolving professional guidelines.

Desing

Cross-sectional study.

Setting

US commercial insurance beneficiaries from Market-Scan (late 2015 to 2018).

Study design

We included women with GDM, singleton gestations, 15-51 years of age on pharmacotherapy. The exposure was pharmacy claims for metformin, glyburide and insulin.

Main outcomes

Pharmacotherapy for GDM with either oral agent, metformin or glyburide, compared with insulin as the reference, and secondarily, consequent treatment modification (addition and/or change) to metformin, glyburide or insulin.

Re

SUBMITTER: Venkatesh KK 

PROVIDER: S-EPMC8752504 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature