Oncologic outcomes according to the location and status of resection margin in pancreas head cancer: role of radiation therapy in R1 resection.

ABSTRACT:

Purpose

The clinical significance of margin status in pancreatic head cancer is still controversial due to the nonstandardized definition of R status and pathologic reporting. This study aims to evaluate the impact of the margin status including location and the role of radiation therapy in pancreatic head cancer.

Methods

A total of 314 patients who underwent curative-intent surgery for pancreatic head cancer between 2010 and 2017 were analyzed. Demographics, survival, and local recurrences were compared according to 2 definitions: 0-mm R1 as direct involvement and 1-mm R1 as close resection margin less than 1 mm. The specific margins were divided into 4 groups according to the location around the pancreas: pancreas transection, anterior surface, posterior surface, and vesse

SUBMITTER: Sohn HJ 

PROVIDER: S-EPMC8753382 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature