Respiratory system compliance at the same PEEP level is similar in COVID and non-COVID ARDS.

ABSTRACT:

Background

The comparison of respiratory system compliance (C_rs) between COVID and non-COVID ARDS patients has been the object of debate, but few studies have evaluated it when considering applied positive end expiratory pressure (PEEP), which is one of the known determinants of C_rs itself. The aim of this study was to compare C_rs taking into account the applied PEEP.

Methods

Two cohorts of patients were created: those with COVID-ARDS and those with non-COVID ARDS. In the whole sample the association between C_rs and type of ARDS at different PEEP levels was adjusted for anthropometric and clinical variables. As secondary analyses, patients were matched for predicted functional residual capacity and the same association was assessed

SUBMITTER: Fusina F 

PROVIDER: S-EPMC8753591 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature