Serum interleukin-30 level in patients with psoriasis and its correlation with psoriasis severity: a case-control study.

ABSTRACT:

Objectives

To examine the serum levels of interleukin (IL)-30 in patients with psoriasis and evaluate the correlations with the Psoriasis Area and Severity Index (PASI).

Methods

Serum was collected from 26 patients with psoriasis and 26 healthy controls in a case-control setting, and the level of IL-30 was determined using an enzyme-linked immunosorbent assay. Statistical analysis of the IL-30 levels among groups and further correlation analyses of IL-30 levels with PASI scores were performed.

Results

A significant increase in the level of IL-30 in patients with psoriasis compared with healthy controls was observed. In addition, a positive correlation between the IL-30 concentration and PASI scores was found in patients with psoriasis.

Conclusion

IL-30 is presu

SUBMITTER: Omar NS 

PROVIDER: S-EPMC8753790 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature