Validation of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis as the Cause of End-Stage Renal Disease in the US Renal Data System.

ABSTRACT:

Objective

The objective of this study was to validate the diagnosis of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) as the primary cause of end-stage renal disease (ESRD) in the US Renal Data System (USRDS).

Methods

We identified patients with ESRD in the Mass General Brigham (MGB) health care system who were enrolled in the USRDS. The health records of those with AAV listed as the primary cause of ESRD in the USRDS were reviewed to confirm the diagnosis and estimate positive predictive value (PPV). Sensitivity was estimated by evaluating the primary cause of ESRD listed in the USRDS for patients with ESRD due to AAV in the MGB AAV cohort.

Results

We identified 89 MGB patients with ESRD due to AAV in the USRDS. Of these, 85 cases were confirm

SUBMITTER: Cook CE 

PROVIDER: S-EPMC8754012 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature