Molecular and Antigenic Characterization of Avian H9N2 Viruses in Southern China.

ABSTRACT: The H9N2 subtype avian influenza virus (AIV) has become endemic in poultry globally; however due to its low pathogenicity, it is not under primary surveillance and control in many countries. Recent reports of human infection caused by H9N2 AIV has increased public concern. This study investigated the genetic and antigenic characteristics of H9N2 AIV isolated from local markets in nine provinces in Southern China from 2013 to 2018. We detected an increasing annual isolation rate of H9N2 AIV. Phylogenetic analyses of hemagglutinin (HA) genes suggests that isolated strains were rooted in BJ94 lineage but have evolved into new subgroups (II and III), which derived from subgroup I. The estimated substitution rate of the subgroup III strains was 6.23 × 10^-3 substitutions/site/year, wh

SUBMITTER: Yan W 

PROVIDER: S-EPMC8754122 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature