Chronic kidney disease biomarkers and mortality among older adults: A comparison study of survey samples in China and the United States.

ABSTRACT:

Objectives

Among older adults in China and the US, we aimed to compare the biomarkers of chronic-kidney-diseases (CKD), factors associated with CKD, and the correlation between CKD and mortality.

Setting

China and the US.

Study design

Cross-sectional and prospective cohorts.

Participants

We included 2019 participants aged 65 and above from the Chinese Longitudinal Healthy Longevity Study (CLHLS) in 2012, and 2177 from US National Health and Nutrition Examination Survey (NHANES) in 2011-2014.

Outcomes

Urinary albumin, urinary creatinine, albumin creatinine ratio (ACR), serum creatinine, blood urea nitrogen, plasma albumin, uric acid, and estimated glomerular filtration rate (eGFR). CKD (ACR ≥ 30 mg/g or eGFR< 60 ml/min/1.73m2) and mortality.

Analytical

SUBMITTER: Miao H 

PROVIDER: S-EPMC8754291 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature