Multivitamin Use and Overall and Site-Specific Cancer Risks in the National Institutes of Health-AARP Diet and Health Study.

ABSTRACT:

Background

Multivitamins are among the most commonly used supplements in the United States, but their effectiveness in preventing cancer remains unclear.

Objectives

We prospectively examined the association between multivitamin use and risks of overall and site-specific cancer in a large, well-characterized cohort to ascertain potential preventive or harmful relationships.

Methods

We examined 489,640 participants ages 50-71 in the NIH-American Association of Retired Persons (AARP) Diet and Health Study who were enrolled from 1995 to 1998. We linked to 11 state cancer registries in order to identify incident cancers. Multivitamin use was assessed by a baseline questionnaire. Cox proportional hazards regression models of multivitamin use were used to estimate HRs and 95

SUBMITTER: Lim JE 

PROVIDER: S-EPMC8754570 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature