Genetic risk for obesity and the effectiveness of the ChooseWell 365 workplace intervention to prevent weight gain and improve dietary choices.

ABSTRACT:

Background

It is unknown whether behavioral interventions to improve diet are effective in people with a genetic predisposition to obesity.

Objectives

To examine associations between BMI genetic risk and changes in weight and workplace purchases by employees participating in a randomized controlled trial of an automated behavioral workplace intervention to promote healthy food choices.

Methods

Participants were hospital employees enrolled in a 12-mo intervention followed by a 12-mo follow-up. Hospital cafeterias utilized a traffic-light labeling system (e.g., green = healthy, red = unhealthy) that was used to calculate a validated Healthy Purchasing Score (HPS; higher = healthier). A weighted genome-wide BMI genetic score was generated by summing BMI-increasing allele

SUBMITTER: Dashti HS 

PROVIDER: S-EPMC8755032 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature