Inflammatory status, body composition and ethnic differences in bone mineral density: The Southall and Brent Revisited Study.

ABSTRACT: Ethnic differences in bone mineral density (BMD) and fracture risk are well-described; the aim of this study was to investigate whether central adiposity or inflammatory status contribute to these ethnic differences in BMD in later life. The Southall and Brent Revisited study (SABRE) is a UK-based tri-ethnic cohort of men and women of European, South Asian or African Caribbean origin. At the most recent SABRE follow-up (2014-2018), in addition to measures of cardiometabolic phenotype, participants had dual-energy X-ray absorptiometry (DXA) bone and body composition scans. Multiple linear regression was used to determine whether markers of body composition, central adiposity or inflammatory status contributed to ethnic differences in BMD. In men and women, age- and height-adjusted BMD at al

SUBMITTER: Durdin R 

PROVIDER: S-EPMC8755916 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature