Allostatic Load in Cancer: A Systematic Review and Mini Meta-Analysis.

ABSTRACT:

Background

Individuals with cancer experience stress throughout the cancer trajectory. Allostatic load (AL), a cumulative multi-system measure, may have a greater value in stress assessment and the associated biological burden than individual biomarkers. A better understanding of the use of AL and its operationalization in cancer could aid in early detection and prevention or alleviation of AL in this population.

Purpose

To consolidate findings on the operationalization, antecedents, and outcomes of AL in cancer.

Methods

Seven databases (CINAHL, Ovid MEDLINE, Web of Science, APA PsycInfo, Scopus, Embase, and Cochrane CENTRAL) were searched for articles published through April 2020. The NIH tools were used to assess study quality.

Results

Twelve studies met incl

SUBMITTER: Mathew A 

PROVIDER: S-EPMC8755951 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature