Methodological problems of SARS-CoV-2 rapid point-of-care tests when used in mass testing.

ABSTRACT: The aim of the current study is to perform model calculations on the possible use of SARS-CoV-2-rapid point-of-care tests as mass tests, using the quality criteria extracted from evidence-based research as an example for the Federal Republic of Germany. In addition to illustrating the problem of false positive test results, these calculations are used to examine their possible influence on the 7-day incidence. For a substantial period of time, this parameter formed the decisive basis for decisions on measures to protect the population in the wake of the COVID pandemic, which were taken by the government. Primarily, model calculations were performed for a base model of 1,000,000 SARS-CoV-2-rapid point-of-care tests per week using various sensitivities and specificities reported in the liter

SUBMITTER: Hirsch O 

PROVIDER: S-EPMC8755956 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature