Hematuria in anticoagulated patients with atrial fibrillation and urologic cancer.

ABSTRACT:

Background

Based on their renal excretion, direct oral anticoagulants (DOACs) may increase the risk of hematuria in patients with atrial fibrillation (AF) and urologic cancer compared with vitamin K antagonists.

Objectives

To examine the risk of bleeding associated with DOAC versus warfarin in patients with AF and urologic cancer.

Methods

We conducted a Danish nationwide cohort study with individually linked registry data on patients with AF and active or a history of urologic cancer. We calculated crude rates per 100 person-years of hospital episodes of major bleeding and hematuria. We then compared rates of hematuria during the year after initial oral anticoagulation filled prescription by treatment regimen using inverse probability of treatment weighting and Cox re

SUBMITTER: Ording AG 

PROVIDER: S-EPMC8756162 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature