Neuron segmentation using 3D wavelet integrated encoder-decoder network.

ABSTRACT:

Motivation

3D neuron segmentation is a key step for the neuron digital reconstruction, which is essential for exploring brain circuits and understanding brain functions. However, the fine line-shaped nerve fibers of neuron could spread in a large region, which brings great computational cost to the neuron segmentation. Meanwhile, the strong noises and disconnected nerve fibers bring great challenges to the task.

Results

In this article, we propose a 3D wavelet and deep learning-based 3D neuron segmentation method. The neuronal image is first partitioned into neuronal cubes to simplify the segmentation task. Then, we design 3D WaveUNet, the first 3D wavelet integrated encoder-decoder network, to segment the nerve fibers in the cubes; the wavelets could assist the deep network

SUBMITTER: Li Q 

PROVIDER: S-EPMC8756182 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature