Astaxanthin protects spinal cord tissues from apoptosis after spinal cord injury in rats.

ABSTRACT:

Background

There is emerging evidence that astaxanthin plays a significant role in protecting neuro-cells from apoptosis after central nervous system injury. Our study examined the effects of astaxanthin on neuro-cell apoptosis after spinal cord injury.

Methods

One hundred and forty-four healthy adult Sprague-Dawley rats were randomly divided into the experimental group, control group, and sham operation group (n=48). Spinal cord injury was induced using the modified Allen method in the control group and the experimental group; while in the sham operation group, the lamina was removed without spinal cord injury. The rats in the experimental group were given astaxanthin (75 mg/kg) by gavage immediately after the operation, and in the other groups were given the same amount of

SUBMITTER: Li S 

PROVIDER: S-EPMC8756234 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature