Macroscopic Banding Pattern of Collagen Gel Formed by a Diffusion-Reaction Process.

ABSTRACT: Shapes and patterns observed in internal organs and tissues are reproducibly and robustly produced over a long distance (up to millimeters in length). The most fundamental remaining question is how these long geometries of shape and pattern form arise from the genetic message. Recent studies have demonstrated that extracellular matrix (ECM) critically participates as a structural foundation on which cells can organize and communicate. ECMs may be a key to understanding the underlying mechanisms of long-distance patterning and morphogenesis. However, previous studies in this field mainly focused on the complexes and interaction of cells and ECM. This paper pays particular attention to ECM and demonstrates that collagen, a major ECM component, natively possesses the reproducible and definite

SUBMITTER: Narita T 

PROVIDER: S-EPMC8756805 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature