Gender-specific clinical risk scores incorporating blood pressure variability for predicting incident dementia.

ABSTRACT:

Introduction

The present study examined the gender-specific prognostic value of blood pressure (BP) and its variability in the prediction of dementia risk and developed a score system for risk stratification.

Materials and methods

This was a retrospective, observational population-based cohort study of patients admitted to government-funded family medicine clinics in Hong Kong between January 1, 2000 and March 31, 2002 with at least 3 blood pressure measurements. Gender-specific risk scores for dementia were developed and tested.

Results

The study consisted of 74 855 patients, of whom 3550 patients (incidence rate: 4.74%) developed dementia over a median follow-up of 112 months (IQR= [59.8-168]). Nonlinear associations between diastolic/systolic BP measurements and th

SUBMITTER: Zhou J 

PROVIDER: S-EPMC8757295 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature