Body Mass Index and Risk of Second Cancer Among Women With Breast Cancer.

ABSTRACT:

Background

Breast cancer survivors are at increased risk for developing second primary cancers compared with the general population. Little is known about whether body mass index (BMI) increases this risk. We examined the association between BMI and second cancers among women with incident invasive breast cancer.

Methods

This retrospective cohort included 6481 patients from Kaiser Permanente Colorado and Washington of whom 822 (12.7%) developed a second cancer (mean follow-up was 88.0 months). BMI at the first cancer was extracted from the medical record. Outcomes included: 1) all second cancers, 2) obesity-related second cancers, 3) any second breast cancer, and 4) estrogen receptor-positive second breast cancers. Multivariable Poisson regression models were used to estimat

SUBMITTER: Feigelson HS 

PROVIDER: S-EPMC8757319 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature