Patterns of chronic and transient hyperkalaemia and clinically important outcomes in patients with chronic kidney disease.

ABSTRACT:

Background

Whether hyperkalaemia in CKD is chronic or transient, and whether this has different outcome implications, is not known.

Methods

This was an observational study of adults with CKD G3-5 from Stockholm, Sweden 2006-11. We examined individual trajectories of potassium from all measurements obtained through routine outpatient care. For each month of follow-up, we created a rolling assessment of the proportion of time in which potassium was abnormal during the previous 12 months. We defined patterns of hyperkalaemia as transient (≤50% of time during the previous year with potassium >5.0 mmol/L) and chronic (>50% of time with potassium >5.0 mmol/L), and examined whether previous hyperkalaemia pattern offers additional predictive value beyond that provided by the most re

SUBMITTER: Trevisan M 

PROVIDER: S-EPMC8757415 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature