Frailty among chronic kidney disease patients on the kidney transplant waiting list: the sex-frailty paradox.

ABSTRACT:

Background

Frailty is defined as decreased physiologic reserve and resistance to stressors that predisposes patients towards poor health results. Its prevalence in chronic kidney disease (CKD) patients who are kidney transplant (KT) candidates is high. Frailty is associated with a higher rate of complications and mortality after transplant. It is unknown whether frailty phenotype differs depending on sex in this population.

Methods

This was a prospective longitudinal study of 455 KT candidates evaluated for frailty by physical frailty phenotype at the time of inclusion on the KT waiting list. Pre-frailty was defined as the presence of two criteria and frailty as three or more criteria. Univariate and multivariate analyses searched for associations of frailty status, frailty

SUBMITTER: Perez-Saez MJ 

PROVIDER: S-EPMC8757431 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature