Effect of Covid-19 Vaccination on Transmission of Alpha and Delta Variants.

ABSTRACT:

Background

Before the emergence of the B.1.617.2 (delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), vaccination reduced transmission of SARS-CoV-2 from vaccinated persons who became infected, potentially by reducing viral loads. Although vaccination still lowers the risk of infection, similar viral loads in vaccinated and unvaccinated persons who are infected with the delta variant call into question the degree to which vaccination prevents transmission.

Methods

We used contact-testing data from England to perform a retrospective observational cohort study involving adult contacts of SARS-CoV-2-infected adult index patients. We used multivariable Poisson regression to investigate associations between transmission and the vaccination status of in

SUBMITTER: Eyre DW 

PROVIDER: S-EPMC8757571 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature