Incidence, Clinical Characteristics and Outcomes of Early Hyperbilirubinemia in Critically Ill Patients: Insights From the MARS Study.

ABSTRACT:

Objective

To investigate the incidence, clinical characteristics and outcomes of early hyperbilirubinemia in critically ill patients.

Design and setting

This is a post hoc analysis of a prospective multicenter cohort study.

Patients

Patients with measured bilirubin levels within the first 2 days after ICU admission were eligible. Patients with liver cirrhosis were excluded.

Endpoints

The primary endpoint was the incidence of early hyperbilirubinemia, defined as bilirubin ≥33 μmol/L within 2 days after ICU admission. Secondary endpoints included clinical characteristics of patients with versus patients without early hyperbilirubinemia, and outcomes up to day 30.

Results

Of 4,836 patients, 559 (11.6%) patients had early hyperbilirubinemia. Compared to pati

SUBMITTER: Juschten J 

PROVIDER: S-EPMC8757589 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature