Meta-Analysis Using NGS Data: The Veillonella Species in Dental Caries.

ABSTRACT: Objectives: In light of recent technological advances in Next-generation sequencing (NGS) and the accumulation of large, publicly available oral microbiome datasets, the need for meta-analysing data on caries microbiome is becoming feasible and essential. A consensus on the identification of enriched organisms in cariogenic dysbiotic biofilms would be reached. For example, members of the Veillonella genus have been detected in caries biofilms, and may have an underestimated contribution to the dysbiotic process. Hence, we aimed to determine the abundance of Veillonella species in dental caries in studies using NGS data. Materials and Methods: Analysis was performed according to the Preferred Reporting Items for Systematic Review and Meta-Analysis (registered at

SUBMITTER: Dame-Teixeira N 

PROVIDER: S-EPMC8757819 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature