Major Molecular Signaling Pathways in Oral Cancer Associated With Therapeutic Resistance.

ABSTRACT: Oral cancer is a sub-category of head and neck cancers that primarily initiates in the oral cavity. The primary treatment option for oral cancer remains surgery but it is associated with massive disfigurement, inability to carry out normal oral functions, psycho-social stress and exhaustive rehabilitation. Other treatment options such as chemotherapy and radiotherapy have their own limitations in terms of toxicity, intolerance and therapeutic resistance. Immunological treatments to enhance the body's ability to recognize cancer tissue as a foreign entity are also being used but they are new and underdeveloped. Although substantial progress has been made in the treatment of oral cancer, its complex heterogeneous nature still needs to be explored, to elucidate the molecular basis for develop

SUBMITTER: Usman S 

PROVIDER: S-EPMC8757854 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature