Evolution of an invasive ductal carcinoma to a small cell carcinoma of the breast: A case report.

ABSTRACT:

Rationale

Small cell carcinoma (SCC) is a rare subtype of breast cancer and presents a complex diagnostic and treatment challenge, due to paucity of data. To the best of our knowledge, most cases of breast SCC reported in the literature describe a de novo breast primary. Our case is unique as it describes the evolution of an invasive ductal carcinoma after treatment into a SCC of the breast.

Patient concerns and diagnosis

We report a case of a 53-year-old female, lifelong non-smoker, who initially presented with breast mass noted on self examination. Breast and axillary lymph node biopsy demonstrated a hormone receptor positive invasive ductal carcinoma with a metastatic T3 lesion.

Intervention

She was treated with first-line palbociclib/letrozole with initial clinica

SUBMITTER: Hussain M 

PROVIDER: S-EPMC8758025 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature