Nutrigenetic variants and response to diet/lifestyle intervention in obese subjects: a pilot study.

ABSTRACT:

Aims

Nutritional and lifestyle interventions can contribute to prevent and treat obesity and its complications; however, genetic background may influence the success of a therapy. The aim of this pilot study is to evaluate the effects of the interaction between nutrigenetic variants and nutritional intervention, as well as the changes in clinical parameters and the adherence to Mediterranean diet (MedDiet) and to physical activity, of 18 overweight or obese subjects affected by T2D or dysglycemia included in a nutritional program.

Methods

The subjects' clinical parameters as well as their PREDIMED score and physical activity levels were recorded and compared at baseline, at 6 months and at the end of the intervention. Rs9939609 in FTO, rs17782313 near MC4R, rs326 in LPL, rs1

SUBMITTER: Franzago M 

PROVIDER: S-EPMC8758637 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature