Determination of antibiotic residues in bovine milk by HPLC-DAD and assessment of human health risks in Northwestern Himalayan region, India.

ABSTRACT: Antibiotic residues in milk affects economics of dairy industry and poses health risks to consumers. This study aimed to assess health risks associated with presence of antibiotics in 173 raw and pasteurized milk sampled from northwestern Himalayan state of India. The oxytetracycline and amoxicillin were quantitatively analyzed using validated HPLC-DAD. Methods were selective and linear (R² > 0.99) with decision limit and detection capability of 1.4 and 0.9 µg/kg and 2.5 and 1.5 µg/kg for oxytetracycline and amoxicillin, respectively. Recoveries ranged from 88-98% with relative standard deviation < 10%. Oxytetracycline and amoxicillin were detected in 8.1% and 1.2% samples, with 1.7% and 1.2% samples exceeding the tolerance limits, respectively. Health risk assessment revealed t

SUBMITTER: Kumar A 

PROVIDER: S-EPMC8758827 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature