Fabrication of a sugar-immobilized fluorescent PMMA shell on a Ni core particle via soap-free emulsion polymerization.

ABSTRACT: Sugar chain immobilized polymer particles having both magnetic and fluorescent properties can be expected to be useful in a wide variety of biomedical applications such as the detection, separation, and purification of proteins, viruses, or bacteria, because sugar chains specifically adsorb them. Since high magnetic responsiveness is required for such applications, we attempted to fabricate core-shell particles consisting of a submicron-sized magnetic core and a thin polymer shell (nano- to dozens of nanometers thick) that incorporates a fluorescent dye, with sugar molecules immobilized on the surface. Soap-free emulsion polymerization using methyl methacrylate (MMA) monomer and potassium persulfate (KPS) initiator in the presence of aminopropyltrimethoxysilane-treated Ni particles, octyl-

SUBMITTER: Yamauchi N 

PROVIDER: S-EPMC8758926 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature