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Multisystem inflammatory syndrome in neonates (MIS-N) associated with SARS-CoV2 infection: a case series.


ABSTRACT: Multisystem inflammatory syndrome in neonates (MIS-N) is hypothesised to be caused either following transplacental transfer of SARS-CoV2 antibodies or antibodies developed in the neonate after infection with SARS-CoV-2. In this paper, we aim to discuss the clinical manifestations, laboratory features, and management of neonates diagnosed with MIS-N. We collated information from five participating hospitals in western India. A cohort of newborn infants presenting with multi-system involvement, along with the presence of SARS-CoV2 antibodies, was identified. Current proposed international diagnostic criteria for MIS-N were used to group the cases into three categories of Most likely, Possible, and Unlikely MIS-N. A total of 20 cases were reported with a diagnosis of MIS-N, all having high ti

SUBMITTER: More K 

PROVIDER: S-EPMC8759431 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature