Prenatal PM_2.5 exposure and neurodevelopment at 2 years of age in a birth cohort from Mexico city.

ABSTRACT:

Background

Recent studies have reported that air pollution exposure may have neurotoxic properties.

Objective

To examine longitudinal associations between prenatal particles less than 2.5 μm in diameter (PM_2.5) exposure and neurodevelopment during the first two years of children's life.

Methods

Analysis was conducted in PROGRESS, a longitudinal birth cohort between 2007 and 2013 in Mexico City. We used satellite data to predict daily PM_2.5 concentrations at high spatial resolution. Multivariate mixed-effect regression models were adjusted to examine cognitive, language and motor scores in children up to 24 months of age (n = 740) and each trimester-specific and whole pregnancy exposure to PM_2.5.

Results

Models adjusted by child

SUBMITTER: Hurtado-Diaz M 

PROVIDER: S-EPMC8759610 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature