Cost-effective proactive testing strategies during COVID-19 mass vaccination: A modelling study.

ABSTRACT:

Background

As SARS-CoV-2 vaccines are administered worldwide, the COVID-19 pandemic continues to exact significant human and economic costs. Mass testing of unvaccinated individuals followed by isolation of positive cases can substantially mitigate risks and be tailored to local epidemiological conditions to ensure cost effectiveness.

Methods

Using a multi-scale model that incorporates population-level SARS-CoV-2 transmission and individual-level viral load kinetics, we identify the optimal frequency of proactive SARS-CoV-2 testing, depending on the local transmission rate and proportion immunized.

Findings

Assuming a willingness-to-pay of US$100,000 per averted year of life lost (YLL) and a price of $10 per test, the optimal strategy under a rapid transmission scenar

SUBMITTER: Du Z 

PROVIDER: S-EPMC8759769 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature