Identification of RAGE and OSM as New Prognosis Biomarkers of Severe Pneumonia.

ABSTRACT:

Objective

To investigate efficiency of RAGE and OSM as new prognosis biomarkers of severe pneumonia.

Methods

Eligible patients were classified into hypoxemia and nonhypoxemia groups. Meanwhile, the same cohort was divided into survival and nonsurvival groups after a post-hospital stay of 30 days. We analyzed risk factors for the hypoxia and death among these patients.

Results

Compared with nonsurvival group, significant increase was noticed in PH, lymphocyte, albumin and platelet level in survival group, while significant decline was noticed in neutrophils, RBC, hemoglobin, hematocrit, creatinine, total bilirubin, CRP, PCT, OSM, RAGE and neutrophils/lymphocyte level. Oxygenation index level was related to APACHE II, LIS, SOFA, NUTRIC score, WBC, neutrophils, lymphocyt

SUBMITTER: Lei J 

PROVIDER: S-EPMC8759921 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature