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Understanding the molecular basis of cardiomyopathy.

ABSTRACT: Inherited cardiomyopathies are a major cause of mortality and morbidity worldwide and can be caused by mutations in a wide range of proteins located in different cellular compartments. The present review is based on Dr. Ju Chen's 2021 Robert M. Berne Distinguished Lectureship of the American Physiological Society Cardiovascular Section, in which he provided an overview of the current knowledge on the cardiomyopathy-associated proteins that have been studied in his laboratory. The review provides a general summary of the proteins in different compartments of cardiomyocytes associated with cardiomyopathies, with specific focus on the proteins that have been studied in Dr. Chen's laboratory.

SUBMITTER: Bang ML

PROVIDER: S-EPMC8759964 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature

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Understanding the molecular basis of cardiomyopathy.

Bang Marie-Louise ML Bogomolovas Julius J Chen Ju J

American journal of physiology. Heart and circulatory physiology 20211119 2

Inherited cardiomyopathies are a major cause of mortality and morbidity worldwide and can be caused by mutations in a wide range of proteins located in different cellular compartments. The present review is based on Dr. Ju Chen's 2021 Robert M. Berne Distinguished Lectureship of the American Physiological Society Cardiovascular Section, in which he provided an overview of the current knowledge on the cardiomyopathy-associated proteins that have been studied in his laboratory. The review provides ...[more]

PMID: 34797172

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Understanding the molecular basis of cardiomyopathy.

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Understanding the molecular basis of cardiomyopathy.

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