Better COVID-19 Intensive Care Unit survival in females, independent of age, disease severity, comorbidities, and treatment.

ABSTRACT: Although male Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) patients have higher Intensive Care Unit (ICU) admission rates and a worse disease course, a comprehensive analysis of female and male ICU survival and underlying factors such as comorbidities, risk factors, and/or anti-infection/inflammatory therapy administration is currently lacking. Therefore, we investigated the association between sex and ICU survival, adjusting for these and other variables. In this multicenter observational cohort study, all patients with SARS-CoV-2 pneumonia admitted to seven ICUs in one region across Belgium, The Netherlands, and Germany, and requiring vital organ support during the first pandemic wave were included. With a random intercept for a center, mixed-effects logistic regression w

SUBMITTER: Meijs DAM 

PROVIDER: S-EPMC8760268 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature