Ontology highlight
ABSTRACT:
SUBMITTER: An N
PROVIDER: S-EPMC8760284 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
An Ni N Li Zhenjie Z Yan Xiaodi X Zhao Hainan H Yang Yajie Y Liu Ruling R Yang Yanyong Y Gao Fu F Li Bailong B Liu Hu H Yuan Hongbin H
Cell death discovery 20220114 1
The lung is one of the most sensitive tissues to ionizing radiation, thus, radiation-induced lung injury (RILI) stays a key dose-limiting factor of thoracic radiotherapy. However, there is still little progress in the effective treatment of RILI. Ras-related C3 botulinum toxin substrate1, Rac1, is a small guanosine triphosphatases involved in oxidative stress and apoptosis. Thus, Rac1 may be an important molecule that mediates radiation damage, inhibition of which may produce a protective effect ...[more]