No-reflow phenomenon and in vivo cholesterol crystals combined with lipid core in acute myocardial infarction.

ABSTRACT:

Background

The release of lipid-laden plaque material subsequent to ST-segment elevation myocardial infarction (STEMI) may contribute to the no-reflow phenomenon. The aim of this study was to investigate the association between in vivo cholesterol crystals (CCs) detected by optical coherence tomography (OCT) and the no-reflow phenomenon after successful percutaneous coronary intervention (PCI) in patients with acute STEMI.

Methods

We investigated 182 patients with STEMI. Based on the thrombolysis in myocardial infarction (TIMI) flow grade after PCI, patients were divided into a no-reflow group (n = 31) and a reflow group (n = 151). On OCT, CCs were defined as thin, high-signal intensity regions within a plaque. A multivariable logistic regression analysis was performed to de

SUBMITTER: Katayama Y 

PROVIDER: S-EPMC8760498 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature