Detection of homologous recombination events in SARS-CoV-2.

ABSTRACT:

Purpose

The COVID-19 disease with acute respiratory symptoms emerged in 2019. The causal agent of the disease, the SARS-CoV-2 virus, is classified into the Betacoronaviruses family. Coronaviruses (CoVs) are a huge family of viruses. Therefore, homologous recombination studies can help recognize the phylogenetic relationships among these viruses.

Methods

In order to detect possible recombination events in SASRS-CoV-2, the genome sequences of Betacoronaviruses were obtained from the GenBank. The nucleotide sequences with the identity ≥ 60% to SARS-CoV-2 genome sequence were selected and then analyzed using different algorithms.

Results

The results showed two recombination events at the beginning and the end of the genome sequence of SARS-CoV-2. Bat-SL-CoVZC21 (GenBank a

SUBMITTER: Lohrasbi-Nejad A 

PROVIDER: S-EPMC8761517 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature