Association Between Neutrophil-Lymphocyte Ratio and Frailty: The Chinese Longitudinal Healthy Longevity Survey.

ABSTRACT: Background: Inflammation has been reported to play an important role in frailty syndrome. The neutrophil-lymphocyte ratio (NLR) has recently emerged as an informative marker for systematic inflammation. However, few studies have examined the association between NLR and frailty. This study aims to examine the association between NLR and frailty in community-dwelling older adults. Methods: Community-dwelling older adults aged ≥ 65 years in the 2011 (n = 2,354) and 2014 (n = 2,458) waves of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) were included. Frailty status was determined using the 38-item frailty index (FI) and categorized into "robust" (FI ≤ 0.1), "pre-frail" (0.1 < FI ≤ 0.21), or "frail" (FI > 0.21). NLR was calculated using a derived formula

SUBMITTER: Xu W 

PROVIDER: S-EPMC8761893 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature