Genomic Insights Into the Population History and Biological Adaptation of Southwestern Chinese Hmong-Mien People.

ABSTRACT: Hmong-Mien (HM) -speaking populations, widely distributed in South China, the north of Thailand, Laos, and Vietnam, have experienced different settlement environments, dietary habits, and pathogenic exposure. However, their specific biological adaptation remained largely uncharacterized, which is important in the population evolutionary genetics and Trans-Omics for regional Precision Medicine. Besides, the origin and genetic diversity of HM people and their phylogenetic relationship with surrounding modern and ancient populations are also unknown. Here, we reported genome-wide SNPs in 52 representative Miao people and combined them with 144 HM people from 13 geographically representative populations to characterize the full genetic admixture and adaptive landscape of HM speakers. We found

SUBMITTER: Liu Y 

PROVIDER: S-EPMC8762323 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature