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Striatal necrosis caused by Lichtheimia ramosa in a neonatal calf.


ABSTRACT: A 12-day-old male calf that did not want breast milk from birth died following neurological signs such as staggering. Postmortem examination revealed bleeding and encephalomalacia in the left striatum and frontal lobe. Histopathologically, necrotic granulomatous encephalitis with numerous fungi was detected. The fungi were positively stained with anti-Rhizomucor mouse monoclonal antibodies. Lichtheimia ramosa was detected in formalin-fixed paraffin-embedded samples of the affected tissue by molecular methods. To the best of our knowledge, striatal necrosis caused by L. ramosa in a neonatal calf has not been reported. This study provides the first evidence of striatal necrosis caused by L. ramosa in a neonatal calf.

SUBMITTER: Iwanaga M 

PROVIDER: S-EPMC8762403 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature

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Striatal necrosis caused by Lichtheimia ramosa in a neonatal calf.

Iwanaga Mikuya M   Kamikawa Ayaka A   Imai Naoto N   Shimada Kaho K   Degawa Yousuke Y   Hanafusa Yasuko Y   Shibahara Tomoyuki T  

The Journal of veterinary medical science 20211028 12


A 12-day-old male calf that did not want breast milk from birth died following neurological signs such as staggering. Postmortem examination revealed bleeding and encephalomalacia in the left striatum and frontal lobe. Histopathologically, necrotic granulomatous encephalitis with numerous fungi was detected. The fungi were positively stained with anti-Rhizomucor mouse monoclonal antibodies. Lichtheimia ramosa was detected in formalin-fixed paraffin-embedded samples of the affected tissue by mole  ...[more]

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