Proteomic Discovery of Noninvasive Biomarkers Associated With Sport-Related Concussions.

ABSTRACT:

Background and objectives

Sport-related concussions affect millions of individuals across the United States each year, and current techniques to diagnose and monitor them rely largely on subjective measures. Our goal was to discover and validate objective, quantifiable noninvasive biomarkers with the potential to be used in sport-related concussion diagnosis.

Methods

Urine samples from a convenience series of healthy control collegiate athletes who had not sustained a concussion and athletes who sustained a concussion as diagnosed by a sports medicine physician within 7 days were collected prospectively and studied. Participants also completed an instrumented single-task gait analysis as a functional measure. Participants were recruited from a single collegiate athletic prog

SUBMITTER: Daisy CC 

PROVIDER: S-EPMC8762586 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature