Difference in oral microbial composition between chronic periodontitis patients with and without diabetic nephropathy.

ABSTRACT:

Background

To investigate the difference in the structural composition of salivary flora between chronic periodontitis patients with and without diabetic nephropathy (DN).

Methods

Thirty salivary samples of 15 chronic periodontitis patients with DN (DN group) and 15 chronic periodontitis patients with diabetes but without DN (DM group) were subjected to pyrosequencing of polymerase chain reaction-amplified 16 s ribosomal RNA genes. After diversity testing, the differential flora were analyzed. The sequencing results were compared with GenBank database to determine the type of differential flora using species composition analysis, hierarchical cluster analysis, principal co-ordinate analysis, and species difference analysis.

Results

There were significant between-group

SUBMITTER: Zhang D 

PROVIDER: S-EPMC8762855 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature