INHBA is a Prognostic Biomarker and Correlated With Immune Cell Infiltration in Cervical Cancer.

ABSTRACT: Background: Inhibin A (INHBA), a member of the TGF-β superfamily, has been shown to be differentially expressed in various cancer types and is associated with prognosis. However, its role in cervical cancer remains unclear. Methods: We aimed to demonstrate the relationship between INHBA expression and pan-cancer using The Cancer Genome Atlas (TCGA) database. Next, we validated INHBA expression in cervical cancer using the Gene Expression Omnibus (GEO) database, including GSE7803, GSE63514, and GSE9750 datasets. Enrichment analysis of INHBA was performed using the R package "clusterProfiler." We analyzed the association between immune infiltration level and INHBA expression in cervical cancer using the single-sample gene set enr

SUBMITTER: Zhao K 

PROVIDER: S-EPMC8764128 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature