Mitonuclear incompatibility as a hidden driver behind the genome ancestry of African admixed cattle.

ABSTRACT:

Background

Africa is an important watershed in the genetic history of domestic cattle, as two lineages of modern cattle, Bos taurus and B. indicus, form distinct admixed cattle populations. Despite the predominant B. indicus nuclear ancestry of African admixed cattle, B. indicus mitochondria have not been found on the continent. This discrepancy between the mitochondrial and nuclear genomes has been previously hypothesized to be driven by male-biased introgression of Asian B. indicus into ancestral African B. taurus. Given that this hypothesis mandates extreme demographic assumptions relying on random genetic drift, we propose a novel hypothesis of selection induced by mitonuclear incompatibility and assess these hypotheses with regard to the current genomic status of African admix

SUBMITTER: Kwon T 

PROVIDER: S-EPMC8764764 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature