Evidence from Drosophila Supports Higher Duplicability of Faster Evolving Genes.

ABSTRACT: The faster rate of evolution of duplicated genes relative to singletons has been well documented in multiple lineages. This observation has generally been attributed to a presumed release from constraint following creation of a redundant, duplicate copy. However, it is not obvious that the relationship operates in this direction. An alternative possibility-that the faster rate of evolution predates the duplication event and the observed differences result from a higher propensity to duplicate in fast-evolving genes-has been tested in primates and in insects. However, these studies arrived at different conclusions and clarity is needed on whether these contrasting results relate to differences in methodology or legitimate biological differences between the lineages selected. Here, we test w

SUBMITTER: Vance Z 

PROVIDER: S-EPMC8765793 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature