Prediction of Outcome After Endovascular Embolectomy in Anterior Circulation Stroke Using Biomarkers.

ABSTRACT: Stroke is a major public health problem that can cause a long-term disability or death due to brain damage. Serious stroke is frequently caused by a large vessel occlusion in the anterior circulation, which should be treated by endovascular embolectomy if possible. In this study, we investigated the use of the brain damage biomarkers tau, NFL, NSE, GFAp, and S100B to understand the progression of nervous tissue damage and their relationship to outcome in such stroke after endovascular treatment. Blood samples were taken from 90 patients pre-treatment and 2 h, 24 h, 48 h, 72 h and 3 months after endovascular treatment. Stroke-related neurological deficit was estimated using the National Institute of Health Stroke Scale (NIHSS) at admission and at 24 h. Neurological outcome was evaluated at

SUBMITTER: Pujol-Calderon F 

PROVIDER: S-EPMC8766380 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature