Identification of stomatal-regulating molecules from de novo arylamine collection through aromatic C-H amination.

ABSTRACT: Stomata-small pores generally found on the leaves of plants-control gas exchange between plant and the atmosphere. Elucidating the mechanism that underlies such control through the regulation of stomatal opening/closing is important to understand how plants regulate photosynthesis and tolerate against drought. However, up-to-date, molecular components and their function involved in stomatal regulation are not fully understood. We challenged such problem through a chemical genetic approach by isolating and characterizing synthetic molecules that influence stomatal movement. Here, we describe that a small chemical collection, prepared during the development of C-H amination reactions, lead to the discovery of a Stomata Influencing Molecule (SIM); namely, a sulfonimidated oxazole that inhibit

SUBMITTER: Toda Y 

PROVIDER: S-EPMC8766585 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature