Posttransplant Diabetes Mellitus and Immunosuppression Selection in Older and Obese Kidney Recipients.

ABSTRACT:

Rationale & objective

Posttransplant diabetes mellitus (DM) after kidney transplantation increases morbidity and mortality, particularly in older and obese recipients. We aimed to examine the impact of immunosuppression selection on the risk of posttransplant DM among both older and obese kidney transplant recipients.

Study design

Retrospective database study.

Setting & participants

Kidney-only transplant recipients aged ≥18 years from 2005 to 2016 in the United States from US Renal Data System records, which integrate Organ Procurement and Transplantation Network/United Network for Organ Sharing records with Medicare billing claims.

Exposures

Various immunosuppression regimens in the first 3 months after transplant.

Outcomes

Development of DM >3 months-

SUBMITTER: Axelrod DA 

PROVIDER: S-EPMC8767140 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature