The landscape of prognostic and immunological role of myosin light chain 9 (MYL9) in human tumors.

ABSTRACT:

Introduction

Recent studies have shown that myosin light chain 9 (MYL9) plays a vital role in immune infiltration, tumor invasion, and metastasis; however, the prognostic and immunological role of MYL9 has not been reported. The purpose of this study was to explore the potential prognostic and immunological roles of MYL9 in human cancers by public datasets mainly including the cancer genome atlas (TCGA) and Gene expression omnibus.

Methods

The expression pattern and prognostic value of MYL9 were analyzed across multiple public datasets in different cancer. The correlations between MYL9 expression and immune infiltration among multiple cancers were analyzed by using the TIMER2.0. The MYL9-related gene enrichment analysis was implemented by mainly using KEGG and GO datasets.

SUBMITTER: Lv M 

PROVIDER: S-EPMC8767521 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature