Ontology highlight
ABSTRACT:
SUBMITTER: Qian HG
PROVIDER: S-EPMC8767542 | biostudies-literature | 2022 Feb
REPOSITORIES: biostudies-literature
Qian Hong-Gang HG Wu Qiong Q Wu Jian-Hui JH Tian Xiu-Yun XY Xu Wei W Hao Chun-Yi CY
Molecular medicine reports 20220111 2
Long non‑coding RNAs can regulate the malignant tumor phenotype either as tumor suppressors or oncogenes. The present study investigated the underlying mechanism of LINC00238 in liver cancer. LINC00238 was identified as a downregulated molecule in The Cancer Genome Atlas liver hepatocellular carcinoma dataset through Gene Expression Profiling Interactive Analysis software. Through gain‑ and loss‑of‑function experiments, LINC00238 was confirmed as a tumor suppressor that could not only decrease c ...[more]